Registration Options

Activity Date: 04/18/2023

Session Time and Location

Date: Tuesday, 04/18/2023

Time: 12:00 PM (view in the schedule)

Room: Centennial IV

Target Audience

If you are a pharmacist, nurse practitioner, or other health care professional involved in the comprehensive medication management of individuals living with mental health and/or substance use disorders, we invite you to participate in this online course.

Session Summary

Treatment of opioid use disorder may include buprenorphine. A limitation of buprenorphine use is that patients must abstain from opioid use for some time prior to initiation therapy to avoid severe, precipitated withdrawal. There are some clinical situations where buprenorphine initiation is not successful. This can include prior unsuccessful initiations, use of illicit fentanyl, and transitioning from methadone. Buprenorphine micro-dosing (low dose) is an initiation strategy that can be utilized in these situations.

Published Research Related to this Session: 
  • Spreen LA, Dittmar EN, Quirk KC, Smith MA. Buprenorphine initiation strategies for opioid use disorder and pain management: A systematic review. Pharmacotherapy. 2022 May;42(5):411-427. doi: 10.1002/phar.2676. Epub 2022 Mar 25. PMID: 35302671; PMCID: PMC9310825.

Faculty Information and Disclosures

Michael Smith, PharmD, FCCP, BCPS

View biographical information and disclosures

Learning Objectives

  1. Recall pharmacology of buprenorphine. 
  2. Discuss quality of evidence of buprenorphine low dose for induction.
  3. Recognize clinical scenarios when buprenorphine low dose can be utilized.

Continuing Education Credit and Disclosures

ACPEThe American Association of Psychiatric Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

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