Thanks to our partnership with Current Psychiatry (CP) published through Quadrant Healthcom Inc., another CPNP Savvy Psychopharmacology article was featured in the April 2016 edition of Current Psychiatry. The goal of this section is to present an evidence-based discussion to guide safe, effective prescribing of psychotropic medications. Elizabeth A. Jackson, PharmD, BCPS, BCPP, Aila J. Spiegel, PharmD, BCPP, and Rebecca L. Graham, PharmD, BCPP, authored this month’s article on When and Why to Initiate Antipsychotic Polypharmacy, and with Which Agents.