Registration Options

Activity Dates: 04/29/2025 - 04/29/2028

Session Time and Location

Date: Tuesday, 04/29/2025

Time: 2:00 PM (view in the schedule)

Room: Regency C-L4

Target Audience

If you are a pharmacist, nurse practitioner, or other health care professional involved in the comprehensive medication management of individuals living with mental health and/or substance use disorders, we invite you to participate in this online course.

Session Summary

This Clinical Pearls session consists of three, 15-minute presentations about unique psych pharmacy patient cases and/or clinical challenges. Each presentation will be recorded, and the three combined sessions are available for 1.0 hour of ACPE credit. 

Pseudoephedrine for Clozapine-Induced Nocturnal Enuresis, presented by Jaden Dickinson, PharmD, BCPP

  1. Review possible mechanism(s) for clozapine-induced nocturnal enuresis.
  2. Identify non-pharmacological and pharmacological strategies that could be implemented for clozapine-induced nocturnal enuresis.

Summary: Clozapine-induced nocturnal enuresis is an often underreported side effect with no FDA-approved treatment options. Existing literature consists primarily of case reports with limited-quality evidence on both pharmacological and non-pharmacological approaches. This clinical pearl presents another successful case of pseudoephedrine use, utilizing a formulation and dosing schedule not previously published.

Aripiprazole Loading Strategy for Acute Mania, presented by Brianne Mosley, PharmD, BCPS, BCPP

  1. Summarize evidence for the safety and efficacy of aripiprazole loading for mania.
  2. Describe strategies to reduce the risk of adverse effects with aripiprazole initiation using a loading dose strategy.

Summary: Aripiprazole monotherapy is recommended as first-line for the treatment of manic episodes of bipolar disorder in adult patients. When compared to alternative pharmacotherapies, aripiprazole is generally considered to have a more favorable side effect profile; however, the medication is underutilized in the inpatient setting. This clinical pearl will review evidence to support a more aggressive initial aripiprazole dosing strategy for acute mania. Clinical pearls to ensure safe implementation of aripiprazole loading strategy will be provided.

Delirious Mania: Navigating Identification, Treatment, and Diagnostic Limbo, presented by Kimberly Ehrhard, PharmD, BCPP

  1. Identify the distinguishing features of delirious mania, including presentation and symptomatology and controversy of diagnosis.
  2. Analyze potential treatment modalities for delirious mania, emphasizing the unique challenges and considerations in management.

Summary: Delirious mania (DM) is a rare and severe psychiatric syndrome characterized by a combination of manic, psychotic, catatonic, and delirious symptoms. Despite its distinct clinical presentation, DM lacks formal diagnostic criteria in both the DSM-5 and ICD-10, complicating accurate identification and management. Misdiagnosis or delayed treatment can worsen symptoms and prolong hospitalization, emphasizing the need for greater clinical awareness. Debate continues over whether DM represents a subtype of bipolar disorder, a form of excited catatonia, or a distinct syndrome. This clinical pearl provides a comprehensive overview of DM, focusing on key diagnostic considerations and evidence-based treatment strategies to improve outcomes.

Faculty Information

Jaden Dickinson, PharmD, BCPP
Brianne Mosley, PharmD, BCPS, BCPP
Kimberly Ehrhard, PharmD, BCPP

View biographical information

Continuing Education Credit and Disclosures

Activity Dates: 04/29/2025 - 04/29/2028
ACPE Contact Hours: 1
ACPE Number: 0284-0000-25-016-H01-P (Knowledge)
Nursing Credit Reminder: Note that ACPE credit is accepted for ANCC Certification Renewal and AANPCB advanced practice provider content. For specific questions related to your organization's acceptance of ACPE continuing education units, please contact your organization directly.

ACPEThe American Association of Psychiatric Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

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