Navigate the complexities of managing mood stabilizers in patients with renal and hepatic disease, where balancing treatment efficacy with safety becomes a critical challenge. This session will cover the pharmacokinetic changes that occur in chronic kidney and liver disease and provide insights into the decision-making process of continuing or discontinuing mood stabilizers in the presence of end organ damage. Learn to adjust dosing effectively and implement monitoring strategies tailored to ensure both safety and therapeutic success in these vulnerable patient populations.
Target Audience
If you are a pharmacist, nurse practitioner, or other health care professional involved in the comprehensive medication management of individuals living with mental health and/or substance use disorders, we invite you to participate in this online course.
Course Requirements
To receive ACPE credit for this session, you must:
- Register for this course.
- Review the full content of the activity and reflect upon its teachings.
- Complete the evaluation at the end of the activity.
- Provide the necessary details in your profile to ensure correct reporting by AAPP to CPE Monitor.
Faculty Information

View biographical information
Shadi Doroudgar, PharmD, APh, BCPS, BCGP, BCPP
Assistant Dean of Enrollment Management; Professor, Clinical and Social Pharmacy Sciences Department
Touro University California College of Pharmacy
Vallejo, CA
Learning Objectives
- Describe pharmacokinetic changes that occur in patients with chronic kidney and liver disease.
- State reasons to continue versus discontinue a mood stabilizer once a patient experiences end organ damage.
- Outline a process for adjusting mood stabilizer doses in patients with chronic kidney or liver disease.
- Discuss strategies to effectively monitor mood stabilizer safety and efficacy in special patient populations.
Continuing Education Credit and Disclosures
Activity Dates: 04/28/2025 - 04/28/2028
ACPE Contact Hours: 1
ACPE Number: 0284-0000-25-011-H01-P (Knowledge)
Nursing Credit Reminder: Note that ACPE credit is accepted for ANCC Certification Renewal and AANPCB advanced practice provider content. For specific questions related to your organization's acceptance of ACPE continuing education units, please contact your organization directly.
The American Association of Psychiatric Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
AAPP owns the copyright, is licensed or has received permissions for use of, or is otherwise permitted to use copyrighted materials within any CPE activity. Authors and speakers are required to obtain necessary copyright permissions for content in CPE activities. AAPP complies with copyright laws and regulations.
View disclaimer and disclosure of off-label use
Off-Label Use: This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA (see faculty information). The opinions expressed in the educational activity do not necessarily represent the views of AAPP and any educational partners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer: Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
View fair balance and integrity statement
It is the policy of AAPP to ensure independence, balance, objectivity, scientific rigor, and integrity in continuing education activities. Those involved in the development of this continuing education activity have made all reasonable efforts to ensure that information contained herein is accurate in accordance with the latest available scientific knowledge at the time of accreditation of this continuing education activity. Information regarding drugs (e.g., their administration, dosages, contraindications, adverse reactions, interactions, special warnings, and precautions) and drug delivery systems is subject to change, however, and the reader is advised to check the manufacturer’s package insert for information concerning recommended dosage and potential problems or cautions prior to dispensing or administering the drug or using the drug delivery systems.
Fair balance is achieved through ongoing and thorough review of all materials produced by faculty, and all educational and advertising materials produced by supporting organizations, prior to educational offerings. Approval of credit for this continuing education activity does not imply endorsement by AAPP for any product or manufacturer identified.