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Registration Options

Activity Date: 04/24/2018

AAPP 2018 registration is closed.

Session Time and Location

The live session is complete.

Target Audience

This course is designed for pharmacists, nurse practitioners or other healthcare professionals involved in the comprehensive medication management of psychiatric and/or neurological patients.

Session Summary

Tuesday, April 24, 2018, 8:30-9:30 AM

Deconstructing the illness of schizophrenia is of particular interest as this heterogeneous disorder may be composed of etiologically distinct disorders with different mechanisms which could all serve as treatment targets for components of the disorder. One specific group with elevated peripheral and central inflammatory response is those with schizophrenia having elevations in antigliadin antibodies (AGA IgG). In addition to high inflammation, this subgroup may be distinct by having lower positive symptoms and high kynurenic acid levels. It remains unclear, however, how these elevations in AGA IgG and immune activation in this subgroup may contribute to the illness and schizophrenia psychopathology; however it may be related to gut permeability or mimicry/cross reactivity to proteins present. This population may represent a subgroup which may have personalized and targeted treatments developed. This talk will discuss the emerging association of inflammation and immune activity in schizophrenia, review the data that helps characterize the subgroup with AGA IgG and present ongoing work for treatment targets and mechanisms of action connecting gluten to schizophrenia. This work suggests that more personalized treatments targeting diet modulation or immune/inflammation may play future roles in schizophrenia treatment.

Course Requirements

To receive ACPE credit for the live session at the Annual Meeting, you must:

  • Sign in (or create a FREE account).
  • Register for this course.
  • Attend and participate in the entire session and reflect upon its teachings.
  • Complete the evaluation at the end of the activity.
  • Provide the necessary details in your profile to ensure correct reporting by AAPP to CPE Monitor.

This course will be provided at the CPNP 2018 Annual Meeting, April 22-25, 2018. Upon successful completion, ACPE credit is reported immediately to CPE Monitor although transcripts can be retrieved by participants online at https://aapp.org/mycpnp/transcript/acpe.

Faculty Information and Disclosures

Learning Objectives

  1. Describe the emerging role of inflammation in schizophrenia.
  2. Discuss ongoing research to characterize subgroup of schizophrenia patients with immune response and inflammation to gluten.
  3. Recognize potential pathophysiologic mechanisms related to an immune response to gluten.
  4. Understand ongoing work for personalizing treatment in this subgroup of schizophrenia with potential gluten sensitivity.

Continuing Education Credit and Disclosures

Activity Date: 04/24/2018
ACPE Contact Hours: 1
ACPE Number: 0284-0000-18-033-L01-P (Knowledge)
Nursing Credit Reminder: Note that ACPE credit is accepted for certification renewal.

ACPEThe College of Psychiatric and Neurologic Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This course provides 1.0 contact hour of knowledge-based continuing education credit from CPNP approved programming.

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