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Xylazine is a nonopioid veterinary anesthetic that is increasingly detected in the illicit drug supply across the United States. Among opioid-overdose deaths, there has been a dramatic increase in the presence of xylazine. It is now a common additive to substances like fentanyl, heroin and cocaine. Fentanyl Adulterated or Associated with Xylazine (FAAX) was declared an emerging threat on April 12, 2023 by the White House Office of National Drug Control Policy. 

Authored by AAPP member Sarah Thomason, PharmD, BCPP, BCACP, FASCP, contents of this pharmacist toolkit include: 

  • Current Trends 
  • Street Names
  • Pharmacology/Pharmacokinetics
  • Harm Reduction
  • References