The nation’s drug overdose epidemic continues to change and become worse. The epidemic affects every state and now is driven by illicit fentanyl, fentanyl analogs, methamphetamine, and cocaine, often in combination or in adulterated forms. More than 107,000 deaths were reported in the United States between December 2020 to December 2021. To respond to this epidemic, the CDC recommends expanding treatment access to life-saving and effective medications for opioid use disorder (MOUD), including buprenorphine, methadone, and naltrexone. This free toolkit provides tips and guidance in the following areas of Buprenorphine Initiation:

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  1. Buprenorphine Treatment
  2. Traditional Buprenorphine Initiation
  3. Low Dose Overlap Initiation
  4. Special Populations
  5. Harm Reduction
  6. Helpful Resources
  7. References