AAPP has issued a statement opposing the Substance Abuse and Mental Health Services Administration’s (SAMHSA) policy change to prohibit the use of federal funds for the purchase of “fentanyl test strips or any other substance test kits, including xylazine and medetomidine test strips, intended for use by people using drugs.” Restricting access to this tool risks reversing progress in overdose prevention at a time when synthetic adulterants continue to drive morbidity and mortality.