What is cannabidiol (CBD)?1,2
Cannabis (or marijuana) has been a controlled substance in the United States since 1970. CBD is one of the main chemicals in cannabis. CBD does not cause the same effect of “getting high” as marijuana because it does not contain the psychoactive ingredient, tetrahydrocannabinol (THC). CBD can be bought in the form of an oil, capsules, shampoo, skin cream, and other formulations.
- U.S. Food & Drug Administration. FDA Regulation of Cannabis and Cannabis-Derived Products: Questions and Answers. [cited March 10, 2022]. In: FDA Regulation of Cannabis and Cannabis-Derived Products: Questions and Answers [Internet]. March 10, 2022. Available from: https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
- Expert Committee on Drug Dependence Fortieth Meeting. CANNABIDIOL (CBD) Critical Review Report. 2018.
- What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD.
- Iffland K, Grotenhermen F. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis Cannabinoid Res. 2017 Jan;2(1):139-154. SAGE Publications. DOI: 10.1089/can.2016.0034.
- Blake R, Valmassy R. Podiatric sports medicine: runner's knee examination form. J Am Podiatry Assoc. 1981 Jul;71(7):397-403. MDPI AG. DOI: 10.7547/87507315-71-7-397.
- Food and Drug Administration, Publi. FDA Boxed Warning for Immediate-Release Opioids. J Pain & Palliat Care Pharmacother. 2016 Apr 2;30(2):141-145. Informa UK Limited. DOI: 10.3109/15360288.2016.1173762.
- Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping products. [cited 2022 May 12]. In: CDC. 2021 Aug 3.
- Thiele EA, Marsh ED, French JA, Mazurkiewicz-Beldzinska M, Benbadis SR, Joshi C, et al. Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2018 Mar;391(10125):1085-1096. Elsevier BV. DOI: 10.1016/s0140-6736(18)30136-3.
- Devinsky O, Cross JH, Laux L, Marsh E, Miller I, Nabbout R, et al. Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome. N Engl J Med. 2017 May 25;376(21):2011-2020. Massachusetts Medical Society. DOI: 10.1056/nejmoa1611618.
- FDA approves first drug comprised of an active ingredient derived from marijuana to treat rare, severe forms of epilepsy. [cited 2019 Sep 20]. In: U.S. Food & Drug Administration [Internet]. 2018 Jun 5. Available from: https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms