HHS announced a $100M pilot funding opportunity to prevent, test for, treat and cure Hepatitis C (HCV) in individuals with substance use disorder (SUD) and/or Serious Mental Illness (SMI). This program is particularly designed to support communities severely affected by homelessness and to gain insights on effective ways to identify patients, complete treatment, cure infections, and reduce reinfection by Hepatitis C (a liver disease caused by the Hepatitis C virus).