Treatment Guidelines: Substance Use Disorders

Alcohol Use Disorder

American Association of Psychiatric Pharmacists (AAPP)

• Pharmacist toolkit: Alcohol use disorder (2023)

American Psychiatric Association (APA)

• Practice guideline for the pharmacologic treatment of patients with alcohol use disorder (2018)

American Society of Addiction Medicine (ASAM)

• Clinical practice guideline on alcohol withdrawal management (2020)

Society for Academic Emergency Medicine (SAEM)

• Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department (2024)

Substance Abuse and Mental Health Services Administration (SAMHSA)

• Medication for the treatment of alcohol use disorder: A brief guide (2015)

World Federation of Societies of Biological Psychiatry (WFSBP)

• Treatment of alcohol use disorders in pregnant women (2019)
• Guidelines for biological treatment of substance and related disorders, part 1: Alcoholism, first revision (2017)

Stimulant Use Disorder

American Association of Psychiatric Pharmacists (AAPP)

• Pharmacist toolkit: Methamphetamine use disorder (2023)

American Society of Addiction Medicine (ASAM) and American Academy of Addiction Psychiatry (AAAP)

• Clinical practice guideline on the management of stimulant use disorder (2024)

Substance Abuse and Mental Health Services Administration (SAMHSA)

• Treatment of stimulant use disorders (2020)
• Treatment for stimulant use disorders (TIP 33) (2021)

Opioid Use Disorder

American Association of Psychiatric Pharmacists (AAPP)

• Pharmacist toolkit: Buprenorphine initiation and dosing strategies (2024)
• Pharmacist toolkit: Medication management of opioid use disorder (2023)

American Society of Addiction Medicine (ASAM)

• National practice guideline for the treatment of opioid use disorder: focused update (2020)

Canadian Institutes of Health Research (CIHR)

• Injectable opioid agonist treatment for opioid use disorder: a national clinical guideline (2019)
• Management of opioid use disorders: A national clinical practice guideline (2018)

College of Family Physicians of Canada

• Managing opioid use disorder in primary care (2019)

National Community Pharmacists Association  (NCPA) / National Association of Boards of Pharmacy (NABP)

• The Pharmacy Access to Resources and Medication for Opioid Use Disorder (PhARM-OUD) Guideline (2024)

Substance Abuse and Mental Health Services Administration (SAMHSA)

• Overdose prevention and response toolkit (2024)
• Opioid-Overdose Reduction Continuum of Care Approach (ORCCA) practice guide (2023)
• Medications for opioid use disorder (2021)
• Clinical guidance for treating pregnant and parenting women with opioid use disorder and their infants (2018)
• Federal guidelines for opioid treatment programs (2015)

World Federation of Societies of Biological Psychiatry (WFSBP)

• Guidelines for the biological treatment of substance use and related disorders, part 2: Opioid dependence (2011)

World Health Organization (WHO)

• Community management of opioid overdose (2014)

Sedative, Hypnotic, or Anxiolytic (Benzodiazepine) Use Disorder

American Association of Psychiatric Pharmacists (AAPP)

• Pharmacist toolkit: Benzodiazepine taper (2023)

Tobacco Use Disorder

US Department of Health and Human Services

• Treating tobacco use and dependence (2008)

US Preventive Services Task Force (USPSTF)

• Interventions for tobacco smoking cessation in adults, including pregnant persons (2021)

Other

American Association of Psychiatric Pharmacists (AAPP)

• Pharmacist toolkit: Harm reduction strategies for people who inject drugs (2022)
• Pharmacist toolkit: Xylazine (2023)

American Psychiatric Association (APA)

• Practice guideline for the treatment of patients with substance use disorders (2006)

British Association of Psychopharmacology (BAP)

• BAP updated guidelines: Evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: Recommendations from BAP (2012)

Substance Abuse and Mental Health Services Administration (SAMHSA)

• Treating substance use disorder in older adults (2020)
• Detoxification and substance abuse treatment (2015)

Veterans Affairs/Department of Defense

• VA/DoD clinical practice guideline for the management of substance use disorders (2021)

World Health Organization (WHO)

• Guidelines for the identification and management of substance use and substance use disorders in pregnancy (2014)

Reviewer 1: Roisin Sabol, PharmD
Reviewer 2: Austin Smith, PharmD, BCPP
2024-2025 AAPP Resident and New Practitioner Committee