The Pleasure Pain Balance in a Dopamine Overloaded World

Course Description

This course offers psychiatric pharmacists a focused overview of dopamine’s role in addiction, highlighting how both substances and behaviors like social media use, overeating, and gambling can disrupt dopamine balance. Learners will explore the concept of dopamine homeostasis and how this understanding can inform evidence-based treatment strategies. Emphasis will be placed on integrating non-pharmacologic approaches to support recovery and long-term stabilization in patients with addictive disorders.

Learning Objectives

  1. Explain the neuroscience of pleasure and pain and what happens in the brain as we repeatedly consume high-dopamine rewards.
  2. Describe how chronic intoxicant exposure disrupts homeostasis, shifting the hedonic set-point toward pain and increasing depression and anxiety.
  3. Identify dopamine fasting as a practical, feasible, and effective way to reset reward pathways.
  4. Review the science of hormesis: The intentional pursuit of pain/discomfort to improve mood and reduce pain.

Target Audience

If you are a pharmacist, nurse practitioner, or other health care professional involved in the comprehensive medication management of individuals living with mental health and/or substance use disorders, we invite you to participate in this course.

Course Requirements

To receive ACPE credit for this session, you must:

  • Register for this course.
  • Review the full content of the activity and reflect upon its teachings.
  • Complete the evaluation at the end of the activity.
  • Provide the necessary details in your profile to ensure correct reporting by AAPP to CPE Monitor.

Continuing Education Credit and Disclosures

Activity Dates: 4/19/2026-4/19/2029
ACPE Contact Hours: 1.0
ACPE Number: 0284-0000-##-###-###-P (Application)
Nursing Credit Reminder: Note that ACPE credit is accepted for ANCC Certification Renewal and AANPCB advanced practice provider content. For specific questions related to your organization's acceptance of ACPE continuing education units, please contact your organization directly.

ACPEThe American Association of Psychiatric Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

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Questions? Contact AAPP.

Off-Label Use: This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA (see faculty information). The opinions expressed in the educational activity do not necessarily represent the views of AAPP and any educational partners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer: Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

It is the policy of AAPP to ensure independence, balance, objectivity, scientific rigor, and integrity in continuing education activities. Those involved in the development of this continuing education activity have made all reasonable efforts to ensure that information contained herein is accurate in accordance with the latest available scientific knowledge at the time of accreditation of this continuing education activity. Information regarding drugs (e.g., their administration, dosages, contraindications, adverse reactions, interactions, special warnings, and precautions) and drug delivery systems is subject to change, however, and the reader is advised to check the manufacturer’s package insert for information concerning recommended dosage and potential problems or cautions prior to dispensing or administering the drug or using the drug delivery systems.

Fair balance is achieved through ongoing and thorough review of all materials produced by faculty, and all educational and advertising materials produced by supporting organizations, prior to educational offerings. Approval of credit for this continuing education activity does not imply endorsement by AAPP for any product or manufacturer identified.