Using the “72-hour Rule” to Expand Rapid, Higher Dose Initiation of Methadone in a Hospital-based Bridge Clinic

Initiating methadone under the 72-hour rule in a low-threshold Bridge Clinic was evaluated in a retrospective review of 97 individuals, showing mean starting doses near 52 mg with rapid titration and a 96.9% successful linkage to an Opioid Treatment Program.