The 2025 Companion Infographic Report: Results from the 2021 to 2025 National Surveys on Drug Use and Health offers a visual presentation of selected estimates from the 2021-2025 National Surveys on Drug Use and Health (NSDUHs). Selected national indicators include substance use, substance use disorders, mental health issues, suicidality, substance use treatment, mental health treatment, and recovery from substance use problems or mental health issues among the noninstitutionalized population aged 12 or older in the United States. This infographic accompanies the more comprehensive NSDUH annual national report.