Migraine and Headaches

American Headache Society (AHS)

• Position Statement Update on calcitonin gene-related peptide-targeting therapies are a first-line option for the prevention of migraine (2024)
• Update on integrating new migraine treatments into clinical practice (2021)
• Acute treatment of migraine in children and adolescents (2019)
• Position statement on integrating new migraine treatments into clinical practice (2018)
• How to apply the AHS evidence assessment of the acute treatment of migraine in adults to your patient with migraine (2016)
• Treatment of cluster headache (2016)
• Management of adults with acute migraine in the emergency department (2016)
• The acute treatment of migraine in adults (2015)

American Academy of Neurology (AAN) 

• Pharmacologic treatment for pediatric migraine prevention (2019)
• Acute treatment of migraine in children and adolescents (2019)
• Botulinum neurotoxin for the treatment of blepharospasm, cervical dystonia, adult spasticity, and headache (2016)
• Pharmacologic treatment for episodic migraine prevention in adults (2012)

American College of Physicians (ACP)

• Pharmacologic treatments of acute episodic migraine headache in outpatient settings: a clinical uidelines from American college of physicians (2025)

College of Family Physicians of Canada (CFP)

• Guideline for primary care management of headache in adults (2015)

European Academy of Neurology (EAN)

• Guidelines on the treatment of cluster headache (2023)
• Guideline on the management of medication-overuse headache (2020)

National Institute for Health and Care Excellence (NICE)

• Headaches in over 12s: diagnosis and management (published 2012; updated 2025)

Veterans Affairs/Department of Defense 

• Clinical practice guideline for management of headache (2023)

Reviewer 1: Trisha Mchugh, PharmD
Reviewer 2: Austin Smith, PharmD, BCPP
2025-2026 AAPP Resident and New Practitioner Committee