Treatment Guidelines: Bipolar Disorder

American Academy of Child & Adolescent Psychiatry

• Practice parameter for the assessment and treatment of children and adolescents with bipolar disorder (2007)

American Academy of Family Physicians (AAFP)

• Bipolar disorders: evaluation and treatment (2021)

American Psychiatric Association (APA)

• Treatment of patients with bipolar disorder (2002)
• Guideline watch (2005)

British Association for Psychopharmacology (BAP)

• Evidence-based guidelines for treating bipolar disorder (2016)

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD)

• Guidelines for the treatment of bipolar disorder: summary and a 2023 update of evidence (2023)
• Recommendations for the management of patients with bipolar disorder with mixed presentations (2021)
• Guidelines for the management of patients with bipolar disorder (2018)

Indian Psychiatric Society (IPS)

• Clinical practice guidelines for the management of bipolar disorder: 2025 update (2025)

National Institute for Health and Care Excellence (NICE)

• Bipolar disorder: assessment and management (2014; updated 2025)

The Royal Australian and New Zealand College of Psychiatrists

• Clinical practice guidelines for mood disorders (2020)

Veterans Affairs/Department of Defense (VA/DoD)

• Clinical practice guideline for management of bipolar disorder (2023)

World Federation of Societies of Biological Psychiatry (WFSBP)

• Acute and long-term treatment of mixed states in bipolar disorder (2017)
• Maintenance treatment of bipolar disorders (2013)
• Acute bipolar depression (2010)
• Treatment of acute mania (2009)

Reviewer 1: Christie Costello, PharmD, BCPS, BCPP 
Reviewer 2: Danielle Dauchot, PharmD, BCPP
2026-2027 AAPP Resident and New Practitioner Committee