MedPage Today (5/14, George) reports, “Children exposed to prenatal antidepressants had an increased risk of autism or attention deficit-hyperactivity disorder (ADHD) that was not significant after adjusting for confounding factors, a systematic review and meta-analysis showed.” Investigators found that “overall, prenatal antidepressant use was associated with a modestly increased risk of neurodevelopmental disorders in offspring (relative risk [RR] 1.13, 95% CI 1.08-1.18, P=0.051),” which “was mainly driven by increased risks for autism (RR 1.69, 95% CI 1.24-2.30, P<0.0001) and ADHD (RR 1.35, 95% CI 1.24-1.47, P<0.0001).” But, “similar associations were found for preconception exposure. They also emerged for paternal use of antidepressants, suggesting the relationships reflected parental mental health and gentics, not antidepressants, the researchers said.”