Revision of From First Dose to Full Effect: Mastering Clozapine Initiation, Adjustments, and Drug Interactions from Wed, 10/08/2025 - 12:51

Sign in (or create a FREE account) to register or access your existing registration.

Course Description

This module provides a deep dive into safe and effective clozapine initiation, titration schedules, and dose adjustments. Learners will explore drug interactions that affect clozapine metabolism and how to interpret plasma levels to guide treatment decisions. Build confidence in managing complex clinical scenarios from day one of clozapine therapy.

This is one of seven modules in the A New Era in Clozapine Management educational series. Complete your complimentary registration now to access this module and 6 other ACPE, AMA, ANCC, and AAPA accredited modules.

Learning Objectives

  1. Describe best practices for initiating and titrating clozapine.
  2. Identify drug interactions that impact clozapine metabolism and efficacy.
  3. Interpret clozapine plasma levels to optimize dosing and manage drug interactions.

Target Audience

We invite you to participate in this online course if you are a pharmacist, physician, nurse practitioner, physician assistant, nurse, or other health care professional involved in the care of individuals with serious mental illness.

Faculty

Jonathan M. Meyer, MD
View biographical information

Jonathan M. Meyer, MD | Voluntary Clinical Professor - Department of Psychiatry, University of California, San Diego 

Dr. Jonathan Meyer is a Voluntary Clinical Professor of Psychiatry at University of California, San Diego, and a Distinguished Life Fellow of the American Psychiatric Association. Dr. Meyer is a graduate of Stanford University and Harvard Medical School, and finished psychiatry residency and fellowships at LA General Medical Center. Dr. Meyer has teaching duties at UC San Diego, is a Senior Academic Advisor to the California Department of State Hospitals, and is a psychopharmacology consultant to the first episode psychosis program at the Balboa Naval Medical Center. Dr. Meyer has lectured and published extensively on psychopharmacology. Along with Dr. Stephen Stahl he is co-author of the Clozapine Handbook published in 2019, The Clinical Use of Antipsychotic Plasma Levels released in 2021, and The Lithium Handbook published in 2023, all three by Cambridge University Press.

Course Requirements

To receive ACPE credit for this session, you must:

  • Register for this course.
  • Complete the pre-test (if applicable) before starting the activity.
  • Review the full content of the activity and reflect upon its teachings.
  • Complete the post-test at the end of the activity no later than the closing activity date.
  • Complete the evaluation at the end of the activity.
  • If necessary, complete the post-test retest no later than the closing activity date.
  • Receive a passing grade (70%).
  • Provide the necessary details in your profile to ensure correct reporting by AAPP to CPE Monitor.

This activity is supported by an educational grant from the Schizophrenia & Psychosis Action Alliance.